This study was undertaken to compare, in an outpatient setting, the relative advantage of two Suboxone® (Bup/Nx) tapering schedules (one rapid and one gradual) following four weeks of Suboxone® stabilization, as reflected by the proportion of participants providing opiate free urines at the end of the taper regimen. In total, 516 participants were randomized to one of two taper schedules, either 7 days or 28 days. The reason for conducting this study was not to advocate for short-term treatment, but to determine the relative ease of using a more rapid vs. a gradual taper should someone need to discontinue Bup/Nx.
Principal Investigator(s)
Walter Ling, M.D.
Director
Integrated Substance Abuse Programs
University of California, Los Angeles
11075 Santa Monica Boulevard
Suite 200
Los Angeles, CA 90025
lwalter@ucla.edu
Participating Sites
- VA New York Harbor Healthcare System, New York
- North Shore - Long Island Jewish Health Systems, New York
- Connecticut Counseling Centers, Inc., Connecticut
- CODA, Inc., Oregon
- Providence Regional Medical Center, Behavioral Health Services, Washington
- Addiction Research and Treatment Services, Colorado
- Coastal Horizons Center, Inc., North Carolina
- Southlight, Inc., North Carolina