Web-delivery of Evidence-Based, Psychosocial Treatment for Substance Use Disorders

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The purpose of this study is to evaluate the effectiveness of including an interactive, web-based version of the Community Reinforcement Approach (CRA) intervention plus incentives targeting drug abstinence and treatment participation as part of community-based, outpatient substance abuse treatment. The trial will randomize individuals entering outpatient treatment for substance use disorders to receive 12 weeks of either: (1) Treatment as Usual (TAU), reflecting standard treatment at the outpatient programs in which participants are enrolled, or (2) a modification of TAU which includes access to the Therapeutic Education System (TES), a computerized psychosocial intervention which combines skills building modules based on CRA with incentives contingent primarily upon abstinence from drugs of abuse and, secondarily, upon completion of TES modules. The primary outcome measure is drug abstinence during active treatment (as measured via urine testing and confirmed via self-report), and the study will also evaluate if improved outcomes are maintained at 3 and 6 months post-intervention.

CTN Protocol ID: 
CTN-0044
DSMB ID: 
DSMB-0044
ClinicalTrials.gov ID: 

Principal Investigator(s)

Edward V. Nunes, Jr., M.D.
Professor of Clinical Psychiatry
Columbia University College of Physicians and Surgeons and New York State Psychiatric Institute
1051 Riverside Drive
Unit 51, Room 3717
New York, NY 10032
nunesed@pi.cpmc.columbia.edu

Static CTPS

Participating Sites